The Guide for the Care and Use of Laboratory Animals (the Guide) recommends that terrestrial mammals be provided space free of urine and feces in which to rest. To evaluate the feasibility of meeting this...
Social housing is recommended for laboratory rats because they are highly social mammals but research constraints or medical issues often demand individual housing and, when social housing is practiced, it typically involves housing with only...
Individual ventilated cages (IVC) have recently been increasing in popularity. Based on the high rates of ventilation with IVCs, we developed 3 hypotheses: first, mice housed in IVCs experience significantly more cold-stress than mice housed...
Individual ventilated cages (IVC) are increasing in popularity. Although mice avoid IVC in preference testing, they show no aversion when provided additional nesting material or the cage is not ventilated. Given the high ventilation rate...
In laboratories, mice are housed at ambient temperatures between 20 and 24 C, which is below their lower critical temperature of 30 C, but comfortable for human workers. Thus, mice are under chronic thermal stress...
Clinical Laboratory Animal Medicine: An Introduction, Fourth Edition offers a user-friendly guide to the unique anatomy and physiology, care, common diseases, and treatment of small mammals and nonhuman primates. Carefully designed for ease of use...
The transportation of mice into a new clean cage after surgery is a standard procedure but might have detrimental effects during the critical post-surgical recovery phase. To analyse the effect of post-surgical housing, female C57BL/6J...
Some laboratory mice gnaw food pellets without ingesting much of the gnawed material, resulting in the production of waste material. The fact that this food grinding behavior is not seen in all individuals of a...
Some laboratory mice gnaw food pellets without ingesting much of the gnawed material, resulting in the production of waste material called orts. The fact that this food grinding behavior is not seen in all individuals...
Repeated blood sampling from laboratory animals is desirable in certain experimental designs and also for reducing the number of animals used in research. Biochemical methods for analysing blood samples require only small blood volumes to...