Mouse

Ciupa, J. 2023. The hard-hitting tooth—Does a scheduled teeth check reduce the number of mice found dead with malocclusion? Animal Technology and Welfare 22(3), 240–241.

Malocclusion is evident around the first 2-5 weeks of age for mice (NC3Rs, 2021). Therefore, it is hypothesised that a regular welfare check, the POST WEAN CHECK (PWC) at 5 weeks would: - significantly increase...

Read more about Ciupa, J. 2023. The hard-hitting tooth—Does a scheduled teeth check reduce the number of mice found dead with malocclusion? Animal Technology and Welfare 22(3), 240–241.

Spalinger, M., Schwarzfischer, M., Niechcial, A. et al. 2023. Evaluation of the effect of tramadol, paracetamol and metamizole on the severity of experimental colitis. Laboratory Animals 57(5), 529–540.

Application of dextran sodium sulfate (DSS) is often used to induce experimental colitis. Current state of the art is to refrain from the use of analgesics due to their possible interaction with the model. However...

Read more about Spalinger, M., Schwarzfischer, M., Niechcial, A. et al. 2023. Evaluation of the effect of tramadol, paracetamol and metamizole on the severity of experimental colitis. Laboratory Animals 57(5), 529–540.

Schelde, K., Rosenjack, J., Sonneborn, C. et al. 2023. A minimally invasive bronchoscopic approach for direct delivery to murine airways and application to models of pulmonary infection. Laboratory Animals 57(6), 611–622.

The laboratory mouse is used extensively for human disease modeling and preclinical therapeutic testing for efficacy, biodistribution, and toxicity. The variety of murine models available, and the ability to create new ones, eclipses all other...

Read more about Schelde, K., Rosenjack, J., Sonneborn, C. et al. 2023. A minimally invasive bronchoscopic approach for direct delivery to murine airways and application to models of pulmonary infection. Laboratory Animals 57(6), 611–622.

Miller, A. L., Leach, M. C. 2023. Determining the preferred liquid reward in adult C57BL/6 mice. Laboratory Animals 57(3), 332–335.

Using food rewards to motivate mice is commonplace in behavioural research. Using a reward which is highly desirable is of benefit, as it can reduce the need to food restrict animals and can encourage higher...

Read more about Miller, A. L., Leach, M. C. 2023. Determining the preferred liquid reward in adult C57BL/6 mice. Laboratory Animals 57(3), 332–335.

Bodnar, M. J., Ratuski, A. S., Weary, D. M. 2023. Mouse isoflurane anesthesia using the drop method. Laboratory Animals 57(6), 623–630.

Anesthesia with isoflurane prior to carbon dioxide euthanasia is recommended as a refinement, but vaporizer access can be limited. An alternative to vaporizers is the ‘drop’ method, introducing a fixed volume of isoflurane into the...

Read more about Bodnar, M. J., Ratuski, A. S., Weary, D. M. 2023. Mouse isoflurane anesthesia using the drop method. Laboratory Animals 57(6), 623–630.

Bárdos, B., Nagy, I., Gerencsér, Z. et al. 2022. Nest material preference of wild mouse species in laboratory housing. Applied Sciences 12(11), 5750.

Our research examined the nest-building characteristics of two mouse species native to Hungary, the mound-building mouse (Mus spicilegus) and the house mouse (Mus musculus), under laboratory housing conditions. In indoor housing, the nest-building material plays...

Read more about Bárdos, B., Nagy, I., Gerencsér, Z. et al. 2022. Nest material preference of wild mouse species in laboratory housing. Applied Sciences 12(11), 5750.

Braden, G. C., Rasmussen, S., Monette, S. et al. 2017. Effects of breeding configuration on maternal and weanling behavior in laboratory mice. JAALAS 56(4), 369-376.

Although numerous studies have evaluated the effect of housing density on the wellbeing of laboratory mice, little is known about the effect of breeding configuration on mouse behavior. The 8th edition of the Guide for...

Read more about Braden, G. C., Rasmussen, S., Monette, S. et al. 2017. Effects of breeding configuration on maternal and weanling behavior in laboratory mice. JAALAS 56(4), 369-376.

Yang, P., Hish, G., Lester, P. A. 2023. Comparison of systemic extended-release buprenorphine and local extended-release bupivacaine-meloxicam as analgesics for laparotomy in mice. JAALAS 62(5), 416–422.

Extended-release (ER) local anesthetics can be used in multi-modal analgesia or in situations in which systemic analgesics may alter animal physiology and thus introduce interpretational confounds. In this study, we compared the analgesic efficacy of...

Read more about Yang, P., Hish, G., Lester, P. A. 2023. Comparison of systemic extended-release buprenorphine and local extended-release bupivacaine-meloxicam as analgesics for laparotomy in mice. JAALAS 62(5), 416–422.

Tirado-Muñiz, N., Spangler, T. L., Van Rooyen, H. et al. 2023. Evaluation of cage mate–induced postsurgical trauma in mice. JAALAS 62(2), 170–178.

Although mice are social animals, individual housing is sometimes requested after surgery. We questioned whether pair-housing mice after surgery resulted in greater trauma to the surgical site as compared with single housing. We further evaluated...

Read more about Tirado-Muñiz, N., Spangler, T. L., Van Rooyen, H. et al. 2023. Evaluation of cage mate–induced postsurgical trauma in mice. JAALAS 62(2), 170–178.

Stuckey, J. E., Makhija, S. D., Reimer, D. C. et al. 2023. Effects of different grades of carbon dioxide on euthanasia of mice (Mus musculus). JAALAS 62(5), 430–437.

Carbon dioxide (CO2) is a conditionally acceptable method for mouse euthanasia, according to the American Veterinary Medical Association Guidelines for the Euthanasia of Animals. In a 2012 Office of Laboratory Animal Welfare (OLAW) webinar, representatives...

Read more about Stuckey, J. E., Makhija, S. D., Reimer, D. C. et al. 2023. Effects of different grades of carbon dioxide on euthanasia of mice (Mus musculus). JAALAS 62(5), 430–437.

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