Circulating cortisol levels are often used to assess the biological stress response in captive primates. Some methods commonly used to collect blood samples may alter the stress response. As such, noninvasive means to analyze cortisol...
For oral glucose tolerance test (OGTT) in mice, multiple blood samples need to be taken within a few hours from conscious mice. Today, a number of essential parameters may be analysed on very small amounts...
When studying pharmacokinetics in rabbits, researchers must often take multiple blood samples from conscious rabbits. Researchers usually collect these samples via the auricular vein, typically through a port or an indwelling catheter. The authors have...
Collection of blood from the submandibular vein allows simple and rapid processing of many animals without anesthesia and facilitates rapid recovery with no signs of pain and discomfort in the mice. Here we compared the...
A large number of methods for obtaining blood from mice have been published. In our facility, saphenous venepuncture is considered the method of choice for bleeding mice and is believed to have a number of...
Blood sampling is one of the most common procedures performed on laboratory animals as part of scientific research. As an ongoing commitment, our institution has identified a need to improve the current blood sampling method...
Step 1 Gently squeeze the animal about halfway towards you. Hold the animal in place for about 1 to 2 seconds.We use this time to talk to the animal calmly in a gentle voice. When...
This study compared 4 bedding substrates (corncob, paper, hardwood chip, and wire-bottomed cage inserts) and 2 routes of blood collection (lateral tail vein and retroorbital sinus) in 6 male C57BL/6NCrl mice. Mice were maintained with...
Positive reinforcement training (PRT) methods can be applied to gain the voluntary cooperation of laboratory primates with the collection of biological samples. Information will be provided on training techniques used and the amount of training...
The impact of operantly training domestic cats to accept jugular blood collections in a dorsally recumbent (novel) position was assessed. Cats were assigned to one of three groups: Group 1 (N = 14): no training...