Refined Mouse Handling The objective of this project was to introduce tunnel handling—a non-aversive alternative to tail handling—to mice during husbandry and routine handling procedures across a large facility with approximately 12,000 mouse cages. The...

Two agencies within the US Department of Health and Human Services have announced plans to move away from the use of animals in research and testing and transition toward nonanimal models. These announcements, however, came...

An important but underacknowledged barrier to reducing and replacing the use of animals in research and testing is that few researchers are trained in how to use non-animal methodologies. To help address this gap, the...

A number of recent articles in the AWI Quarterly have addressed issues related to the use of nonhuman primates in research: from an alleged international monkey-laundering scheme, to a research industry bid to reverse a...

by Raymond Vagell, PhD candidate at Texas State University Cognitive research using nonhuman primates is common, yet little is known about the effects of cognitive research on the animals themselves. This project, funded by an...

by Jeannine Cason Rodgers, enrichment, behavior and training specialist, and Dr. Christopher Cheleuitte-Nieves, senior clinical veterinarian, the Memorial Sloan Kettering Cancer Center and Weill Cornell Medicine; and Eme Chan, student at Cornell University College of...

Every year, AWI provides financial support for the creation and implementation of “refinement” initiatives meant to advance the welfare of animals used in research through improved housing, husbandry, handling, or care. The Refinement Research Award...

Distinguished medical historian Dr. John Parascandola offers an engaging, thought-provoking, and well-researched account of the growth of animal experimentation and the parallel rise of the animal protection movement in the United States and Great Britain...

In a welcome development, non-animal-derived reagents have been approved for endotoxin testing by the United States Pharmacopeia (USP) Microbiology Expert Committee, and the approval is expected to become official in May 2025. As reported in...

As reported this spring in the AWI Quarterly, a company called Safer Human Medicine (SHM) is seeking to build a massive facility in Bainbridge, Georgia, to breed tens of thousands of long-tailed macaques that it...