Refinement Database

Database on Refinement of Housing, Husbandry, Care, and Use of Animals in Research

This database, created in 2000, is updated every four months with newly published scientific articles, books, and other publications related to improving or safeguarding the welfare of animals used in research.

Tips for using the database:

  • This landing page displays all of the publications in the database.
  • Use the drop-down menus to filter these publications by Animal Type, Setting, and/or Topic.
  • Clicking on a parent category (e.g., Rodent) will include publications relating to all the items in that category (e.g., Chinchilla, Gerbil, Guinea Pig, etc.).
  • You may also add a keyword to further narrow your search.
  • Please note that at this time, only publications dated 2010 or later (with some exceptions) can be filtered by Animal Type and Topic, and only publications dated 2020 or later (with some exceptions) can be filtered by Setting. Most publications older than 2010 can only be searched by keyword. 

In nature, animals need to actively engage with the environment in order to prosper in survival and reproduction. Hence, agency is a central adaptive characteristic of animal life. In this paper, I propose that from...

Green odour (a mixture of cis-3-hexenol and trans-2-hexenal), similar to cut grass, has been demonstrated to appease subjects of various species (rats, cattle, humans etc.) subjected to different stressful stimuli. The aim of this study...

Transmission of fear and attenuation of fear within groups of farm animals remain relatively unexplored, despite the importance for human and animal safety. This paper reports the results of two separate experiments, aiming to explore...

Emotional contagion, a basic component of empathy defined as emotional state-matching between individuals, has previously been shown in dogs even upon solely hearing negative emotional sounds of humans or conspecifics. The current investigation further sheds...

Fear reactions in horses are a major cause of horse–human accidents, and identification of effective pathways for reduction in fearfulness can help decreasing the frequency of accidents. For a young mammal, the mother is one...

As (critical) anthropomorphism provides a useful hypothesis for looking at animal behavior, people's reports about how they see animals' emotions can provide a start point in the direction of experiment-oriented studies. It has been shown...

Animals may experience positive affective states in response to their own achievements. We investigated emotional responses to problem-solving in dogs, separating these from reactions to rewards per se using a yoked control design. We also...